Antiviral and anti-inflammatory effects of rosmarinic acid in an experimental murine model of Japanese encephalitis.

نویسندگان

  • Vivek Swarup
  • Joydeep Ghosh
  • Soumya Ghosh
  • Amit Saxena
  • Anirban Basu
چکیده

Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels in infected mice without treatment, at 8 to 9 days postinfection.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 51 9  شماره 

صفحات  -

تاریخ انتشار 2007